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Does the timing of breast cancer surgery in pre-menopausal women affect clinical outcome? : an update

Anushka Chaudhry1, Michael L Puntis1, Panos Gikas1 and Kefah Mokbel1,2*

Author Affiliations

1 Dept. of Breast Surgery, St George's Hospital, University of London, Tooting, UK

2 The Princess Grace Hospitals, 42-52 Nottingham Place, London W1M 3FD, UK

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International Seminars in Surgical Oncology 2006, 3:37 doi:10.1186/1477-7800-3-37

Published: 1 November 2006

Abstract

There is some evidence that breast cancer surgery during the luteal phase in pre-menopausal women is associated with a better clinical outcome, however the evidence for this is still equivocal.

In this paper, after summarizing the normal physiology of the menstrual cycle, we examine how such an association may occur and provide a comprehensive review of the literature in the area.