Open Access Case report

Intraosseous angiosarcoma with secondary aneurysmal bone cysts presenting as an elusive diagnostic challenge

Lung F Tse1, Eugene TH Ek1, John L Slavin3, Stephen M Schlicht4 and Peter FM Choong1,2*

Author Affiliations

1 Department of Orthopaedics, St. Vincent's Hospital, Melbourne, Australia

2 Bone and Soft Tissue Sarcoma Service, Peter MacCallum Cancer Centre, Melbourne, Australia

3 Department of Anatomical Pathology, St Vincent's Hospital, Melbourne, Australia

4 Department of Radiology, St. Vincent's Hospital, Melbourne, Australia

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International Seminars in Surgical Oncology 2008, 5:10 doi:10.1186/1477-7800-5-10

Published: 20 May 2008

Abstract

Angiosarcoma of bone is an exceedingly rare primary bone malignancy that can present as an aggressive osteolytic lesion. Histological diagnosis can be extremely challenging, as the pathological features often resemble that of aneurysmal bone cysts. We report an interesting and peculiar case of an intraosseous angiosarcoma that presented as a diagnostic dilemma and discuss the relevant radiological and pathologic findings.