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Expression levels of the three GEFs studied related to tnm status |
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| Guanine Nucleotide Exchange Factors |
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| TNM status |
TRIO |
VAV1 |
TIAM-1 |
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| 1 |
160 ± 50.5 |
0.41 ± 0.22 |
430 ± 117 |
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| 2 |
116.5 ± 61.6 |
1.28 ± 1.04 |
2613 ± 2245 |
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| 3 |
669 ± 544 |
0.148 ± 0.12 |
2022 ± 1817 |
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tnm = tumour-node-metastasis. TIAM-1 expression increased with tumour-node-metastasis (tnm) status as did Vav1 levels however, Trio expression showed an increase from tnm1 to tnm3 (160 ± 50 tnm1 and 669 ± 554 tnm4 p = 0.39) but a decrease in Trio expression in tnm2 tumours (117 ± 62). | |||
Lane et al. International Seminars in Surgical Oncology 2008 5:23 doi:10.1186/1477-7800-5-23 |
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