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The IHC scoring system of HER2 |
|
| Staining pattern |
Staining score |
|
|
|
| Membrane staining is observed in < 10% of the tumour cells |
0 |
| A partial and faint membrane staining is detected in > 10% of the tumour cells |
1+ |
| A weak to moderate complete membrane staining is detected in > 10% of the tumour cells |
2+ |
| A moderate to strong complete membrane staining is detected in > 10% of the tumour cells |
3+ |
|
Those tumours which score 0 or 1+ are regarded as negative, those scoring 2+ are borderline and 3+ are positive. | |
Subramanian and Mokbel International Seminars in Surgical Oncology 2008 5:9 doi:10.1186/1477-7800-5-9 |
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