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Surgical treatment of a giant tibial high-grade mixofibrosarcoma with preservation of limb function: a case report

Domenico Marotta1*, Marina Angeloni1, Marzia Salgarello2, Maria L Ricciardella1, Byron Chalidis3 and Giulio Maccauro1

Author affiliations

1 Department of Orthopaedic and Traumatology, Catholic University of Rome, Italy

2 Department of Plastic Surgery, Catholic University of Rome, Italy

3 Department of Orthopaedic and Traumatology, University of California, San Francisco, USA

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Citation and License

International Seminars in Surgical Oncology 2009, 6:16 doi:10.1186/1477-7800-6-16

Published: 17 September 2009

Abstract

Myxofibrosarcoma is one of the most common sarcomas in elderly patients showing a slight male prevalence. The tumor is mainly located in lower and upper extremities and rarely in trunk, neck and feet. We present a case of a 84-year-old man referred to our tumour center with a giant and neglected high-grade tibial myxofibrosarcoma in the anteromedial side of tibial mid-diaphysis. Large size lesions in association with older age may jeopardise the maintenance of limb vitality, vascularity and stability.

Authors performed a complete tumour resection, followed by reconstruction of bone and soft tissue defects with cement, plate and a musculocutaneous gastrocnemius flap, in order to cover the underlying bone and promote uneventful healing and perfusion of the operated extremity.

At 2 years postoperatively, limb salvage, good functional outcome and no tumour recurrence were reported while the patient was able to effectively perform the majority of the daily activities.