International Seminars in Surgical Oncology - Latest Comments

GIST with spontaneous raputure

Tomoaki Ando — 2009-10-29T00:00:00Z

We consider that a case of gastrointestinal stromal tumor with spontaneous rupture in the greater omentum is rare and educational.

This technique is excellent

Abdul Basit — 2008-02-25T00:00:00Z

After reading this paper we have used this technique of mastectomy incision for patients that have large axillary and lateral chest wall folds. It works well particularly if the mastectomy incision is designed in a way that it is oblique as opposed to a transverse incision. The other alternative is to use a fish tail incision which we have also used on some occasions. A Fish Tail incision also works well but requires an extra extension of the incision as mentioned in the above paper.

Bedside Biophysical-Semeiotic Diagnosis of Breast Cancer, since initial Stage.

Sergio Stagnaro — 2007-12-06T00:00:00Z

Sirs,

the authors write:"The typical clinical presentation of idiopathic granulomatous mastitis often mimics infection or malignancy". Unfortunately, it's clear that authors ignore Biophysical Semeiotics (1-5) (www.semeioticabiofisica.it). In addition, using breast cancer genetic risk assessment tools and going through the process of assessing breast cancer risk by this expensive way, can answer many women's questions about what puts them at relatively higher or lower risk. Certainly such as evaluation is to expensive for both NHS and single patient, and not applicable on women (and men!, of course) on very large scale.

In fact, based on 51 year-long clinical experience, for all women (and men!), an original clinical assessement may be desirable that in a easy and reliable manner allows to recognize the possible presence of maternally-inherited CAEMH-dependent, Oncological Terrain and oncological Real Risk, conditio sine qua non of cancer (1, 2), without following with genetic testing, but ascertaining especially breast cancer oncological INHERITED “real risk” in well-defined breast quadrant(s), characterized by newborn-pathological, type I, subtype a) i.e., oncological, Endoarteriolar Blocking Devices (1-5). In addition, testing for mutations of breast cancer susceptibility genes or for their diminished expression adds to our ability to assess breast cancer risk at an individual level. Really, we cannot localise in a (or more) mamma quadrant the possible breast cancer risk in BRCA 1 and BRCA 2, as well as a lot of other gene mutations-positive women (and men!). Biophysical Semeiotics (http://www.semeioticabiofisica.it, Breast Cancer in Practical Application; Oncological Terrain) allows doctor to recognize firstly oncological terrain in a quantitative way, and then, bu “not” in all cases, of course, breast cancer real risk: individuals with oncological terrain do not show generally real risk in all biological systems (3). Interestingly, the absence of both Oncological Terrain and breast oncological “Real Risk”, the later in a subject with Oncological Terrain, excludes beyond every doubt the possibility of occurrence of breast cancer (2, 3). As a consequence, we can perform nowadays an efficacious clinical, primary prevention of breast cancer (4), on very large scale, based on the Single Patient Based Medicine (5-10), as suggests also Planning for the EU public Health Portal at URL:

http://www.google.it/search?q=cache:U5A-DtWmRDsJ:europa.eu.int/comm/health/ph_information/documents/ev_20030710_co01_en.pdf+single+patient+based+medicine+and+stagnaro&hl=it&ie=UTF-8 Pg 36.

Finally, “real” sentinel limphonodes are trigger-points for autoimmune syndrome (3)

References

1) Stagnaro Sergio. There is another clinical, and overlooked tool, reliable in breast cancer prognosis evaluation , 2005. http://www.biomedcentral.com/1471-2407/5/70/comments#204473

2) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno oncologico. Travel Factory SRL., Roma, 2004.

http://www.travelfactory.it/semeiotica_biofisica.htm

3) Stagnaro-Neri M., Stagnaro S. Cancro della mammella: : prevenzione primaria e diagnosi precoce con la percussione ascoltata. Gazz. Med. It.; Arch. Sc. Med. 152, 447, 1993.

4) Stagnaro S. Lettera aperta al Ministro della Salute, Prof. G. Sirchia, sulla prevenzione primaria clinica del cancro mammario.

http://www.katamed.it/Notizia.asp?id=8094&lingua=IT&idcat=999;

http://xoomer.virgilio.it/piazzetta/professione/professione.htm

http://www.ilpungolo.com/site/leggi.asp?NWS=2390&IDS=10.

http://bmj.bmjjournals.com/cgi/eletters?lookup=by_date&days=1#72216 27 August 2004

5) Stagnaro S., Stagnaro-Neri M. Single Patient Based Medicine.La Medicina Basata sul Singolo Paziente: Nuove Indicazioni della Melatonina. Travel Factory SRL., Roma, 2005. http://www.travelfactory.it/semeiotica_biofisica.htm

6) Stagnaro S. Newborn-pathological Endoarteriolar Blocking Devices in Diabetic and Dislipidaemic Constitution and Diabetes Primary Prevention. The Lancet. March 06 2007. http://www.thelancet.com/journals/lancet/article/

PIIS0140673607603316/comments?totalcomments=1

7) Stagnaro Sergio. There is another clinical, and overlooked tool, reliable in breast cancer prognosis evaluation , 2005. http://www.biomedcentral.com/1471-2407/5/70/comments#204473

8) Stagnaro Sergio. "Genes, Oncological Terrain, and Breast Cancer" World Journal of Surgical Oncology., 2005, http://www.wjso.com/content/3/1/45/comments#205475

9) Stagnaro Sergio. Bed-Side Evaluating Breast Cancer Real Risk. World Journal of Surgical Oncology. 2005, 3:67 doi:10.1186/1477-7819-3-67. 2005

10) Stagnaro Sergio Mitochondrial Bed-Side Evaluation: a new Way in the War against Cancer (21 December 2005). Cancer Cell International http://www.cancerci.com/content/5/1/34/comments#218502

Oncological Terrain and Inherited Oncological Real Risk: New Way in Malignancy Primary Prevention and early Diagnosis.

Sergio Stagnaro — 2007-12-06T00:00:00Z

Editors,

the paper's authors write "Ultrasound (US), Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are widely used in the clinical diagnosis of parotid gland tumors and their efficacy in identifying benign lesions is well documented" (1). And then? Unfortunately, these italian Colleagues ignore Biophysical Semeiotics (www.semeioticabiofisica.it), that allows doctors to recognize at the bedside - since birth - Oncological Terrain "and" Inherited oncological Real Risk in every biological systems (2-8). In fact, all around the world authors ignore or overlook the existence of Oncological Terrain (http://www.semeioticabiofisica.it) as well as bed-side recognizing cancer inherited “real” risk, in a quantitative way (2-8).

Consequently, all authors think "wrongly" that “all” individuals must urdergo to cancer markers and other screening measures, as those cited in the article, therefore spending uselessly NHS money, and physician’s energy and time, because physicians think ERRONEOUSLY that everybody can be involved by malignacy. As a matter of fact, a subject can be involved by Oncological Terrain, even with or without precise location of “congenital cancer real risk” in a well defined tissue (“ab posse ad esse non licet illatio”, Kant, Kritik der reinigen Vernunft) (5). I think that because congenital functional mitochondrial cytopathology is overlooked, "conditio sine qua non" of the most frequent and dangerous human disorders, including malignancies, current clinical researches are fundamentally biased. In other words, one does not consider the existence or assess the seriousness as well as the location of Congenital Acidosic Enzyme-Metabolic Histangiopathy (in above-cited web-site), conditio sine qua non of both Oncological Terrain and, consequently cancer “real risk” (2-8). In fact, both environmental risk factors and every drug, including, e.g., oestrogens, suggested as a risk factor for breast cancer, "could" influence some human biological functions and/or bring about different disorders, such as cancers, exclusively in relation to both the presence and intensity of CAEMH in a well-defined biological system. Before all sophysticated semeiotics, as indicated by the authors, physicians have to performe an accurate, up-dated, physical examination, reliable to recognize Oncological Terrain “and” Inherited (sic!) Oncological Real Risk, in our case obviously in the parotid gland! Under such as condition I utilize Coniugated Melatonin, according to Di Bella-Ferrari, associated with NIR-LED local applications (2, 3,5).

In conclusion, we need at first (i.e., starting whatever screening or research) to investigate the presence and intensity of CAEMH in the "tested" population, i.e. in "every", "single" patient, and soon thereafter assessing presence, intensity of the "Oncological Terrain", and the precise location of Congenital cancer “real risk”, both always develop on the basis of the above -mentioned congenital mitochondrial cytopathology. In fact, without this alteration of psycho-neuro-endocrine-immunological system, oncogenesis is not possible, as allows me to state a 46-year-long clinical experience with Biophysical Semeiotics, Single Patient Based Medicine theory is based on (7). The importance of the above-mentioned congenital constitution should not be overlooked, particularly when we assess a "possible" risk factor for cancer and then for cancer screening.

1) Piscioli Irene, et al. Epithelial-myoepithelial carcinoma of the parotid gland, unusual malignancy radiologically simulating a benign lesion: case report. International Seminars in Surgical Oncology 2007, 4:25doi:10.1186/1477-7800-4-2

2) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeiotica Biofisica. Il Terreno Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it/semeiotica_biofisica.htm

3) Stagnaro-Neri M., Stagnaro S. Cancro della mammella: prevenzione primaria e diagnosi precoce con la percussione ascoltata. Gazz. Med. It. – Arch. Sc. Med. 152, 447, 1993

4) Stagnaro Sergio. GPs , Biophysical Semeiotics, and bedside cancer diagnosis. 08 July 2007, International Seminar of Surgical Oncology, http://www.issoonline.com/content/4/1/11/comments#281539 . 2007

5) Stagnaro S. Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it/semeiotica_biofisica_2.htm

6) Sergio Stagnaro. Mitochondrial Bed-Side Evaluation: a new Way in the War against Cancer (21 December 2005). Cancer Cell International http://www.cancerci.com/content/5/1/34/comments#218502

7) Stagnaro S., Stagnaro-Neri M., Single Patient Based Medicine.La Medicina Basata sul Singolo Paziente: Nuove Indicazioni della Melatonina. Travel Factory, Roma, 2005. http://www.travelfactory.it/libro_singlepatientbased.htm

8) Stagnaro Sergio. Reale Rischio Semeiotico-Biofisico. I dispositivi Endoarteriolari di Blocco neoformati-patologici, tipo I, sottotipo a) oncologici e b) aspecifici. Ed Travel Factory, Roma www.travelfactory.it, in press.

GPs , Biophysical Semeiotics, and bedside cancer diagnosis.

Sergio Stagnaro — 2007-07-08T00:00:00Z

Sirs,

this interesting case history accounts for the reason that GPs must study Biophysical Semeiotics, at least its essential technical aspects, first of all, auscultatory percussion of the stomach (www.semeioticabiofisica.it, Technical Page N°1). In fact, in a few minutes doctors would exclude in patients like this whathever coronary disorder (1-3). In addition, detecting intense Oncological Terrain, conditio sine qua non of malignancy, both solid and liquid, and subsequently Oncological Real Risk in the precise skeletral muscle, associated with the numerous biophysical signs of malignancy, illustrated also in above-cited website (3), diagnosis was surely made rapidly at the bedside. In doing that, i.e., in detecting these biophysical semeiotic signs (Retyculo-Endothelial System Hyperfunction Syndrome, Anthybody Synthesis Acute Syndrome, Acute Phase Protein Syndrome, a.s.o., it is necessary the knowledge of stomach auscultatory percussion. Certainly, for applying other refined methods, among them "quantitative" diagnosis of disorder real risk, based on microcirculatory remodelling, characterized by newborn-pathological, type I, subtype a, and b Endoarteriolar Devices (4), physician has to be skilled in the new physical semeiotics.

References

1) Stagnaro-Neri M., Stagnaro S., Deterministic Chaos, Preconditioning and Myocardial Oxygenation evaluated clinically with the aid of Biophysical Semeiotics in the Diagnosis of ischaemic Heart Disease even silent. Acta Med. Medit. 13, 109, 1997.

2) Stagnaro S. A clinical efficacious maneouvre, reliable in bed-side diagnosing coronary artery disease, even initial or silent, as well as “heart coronary risk”. 3rd TCVC Argentine Congress of Cardiology, September 2003 . http://www.fac.org.ar/tcvc/marcoesp/marcos.htm

3) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno oncologico”. Travel Factory SRL., Roma, 2004. http://www.travelfactory.it/

semeiotica_biofisica.htm

4)Stagnaro Sergio. The Lancet. March 06 2007 Newborn-pathological Endoarteriolar Blocking Devices in Diabetic and Dislipidaemic Constitution and Diabetes Primary Prevention. http://www.thelancet.com/journals/lancet/article/PIIS0140673607603316/

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Case Report on Renal Cell Carcinoma cutaneous metastasis

GURPREET SINGH-RANGER MSc MS FRCS(Eng) — 2006-09-16T00:00:00Z

This article was very well written an encapsulates the value of reporting this unusual presentation of renal carcinoma metastasis online.

Immediate access of the report and its good quality images gives the potential for clinicians worldwide to recognise this lesion, and reference their diagnosis accurately.

Congratulations to the authors on an excellent short paper.