http://www.issoonline.com The most accessed research articles published by International Seminars in Surgical Oncology 2009-11-08T00:00:00Z This is an RSS newsfeed from BioMed Central It is intended to be used with an RSS reader. For more information about RSS newsfeeds from BioMed Central, visit http://www.biomedcentral.com/info/about/rss/ Radiation induced angiosarcomas (RIA) can affect breast cancer patients who had radiotherapy following conservative breast surgery. They are very rare tumors and often their diagnosis is delayed due to their benign appearance and difficulty in differentiation from radiation induced skin changes. Therefore it is very important that clinicians are aware of their existence. We report here a case of RIA followed by discussion and review of literature. http://www.issoonline.com/content/3/1/26 M Tahir P Hendry L Baird N Qureshi D Ritchie P Whitford International Seminars in Surgical Oncology 2006, 3:26 2006-09-11T00:00:00Z doi:10.1186/1477-7800-3-26 International Seminars in Surgical Oncology 1477-7800 3 26 2006-09-11T00:00:00Z XML Breast papilloma is a term that describes an intraductal papillary configuration of the mammary epithelium on macroscopic or microscopic examination. It includes solitary intraductal papillomas, multiple papillomas, papillomatosis, and juvenile papillomatosis (JP).Recent advances in mammary ductoscopy (MD) have raised new possibilities in the diagnosis and treatment of breast papillomas. This technique represents an important diagnostic adjunct in patients with pathological nipple discharge (PND) by allowing direct visualisation and biopsy of intraductal lesions and guiding duct excision surgery.Treatment of breast papillomas often entails surgical duct excision for symptomatic relief and histopathological examination. Recently, more conservative approach has been adapted. MD-assisted microdochectomy should be considered the procedure of choice for a papilloma-related single duct discharge. Furthermore, there is increasing evidence that MD has the potential to reduce the number of duct excision procedures and minimise the extent of surgical resection. Imaging-guided vacuum-assisted core biopsy can be diagnostic and therapeutic for papillomas seen on mammography and/or ultrasound.Patients with multiple papillomas do have an increased risk of developing cancer and should be kept under annual review with regular mammography (preferably digital mammography) if treated conservatively. Magnetic resonance (MR) can be also used in surveillance in view of its high sensitivity. Because the risk is small, long term and affects both breasts, long-term follow-up is more appropriate than prophylactic mastectomy. Patients who prove to have solitary duct papilloma have insufficient increase in the risk of subsequent malignancy to justify routine follow-up. http://www.issoonline.com/content/3/1/1 Wail Al Sarakbi Dawit Worku Pedro Escobar Kefah Mokbel International Seminars in Surgical Oncology 2006, 3:1 2006-01-17T00:00:00Z doi:10.1186/1477-7800-3-1 International Seminars in Surgical Oncology 1477-7800 3 1 2006-01-17T00:00:00Z XML A case of a thymic neuroendocrine tumor and the interpretation problems in a post-surgical Somatostatin Receptor Scintigraphy are presented. In a 53-year-old man with superior vena cava obstruction syndrome an atypical carcinoid of the thymus (neuroendocrine carcinoma of intermediate grade 2), was found at surgery.During his first year of follow-up a Somatostatin Receptor Scintigraphy was recommended. An area of abnormal concentration of the radiopharmaceutical was revealed in the mediastinum at this time.A thorough understanding of the mechanisms of the radiopharmaceutical uptake and of the various clinical settings in which uptake can occur are essential for a proper evaluation of the scintigraphic findings and result in the optimal use of this valuable modality.The literature review provides an overview of this rare type of tumor and insight into the clinical significance of Somatostatin Receptor Scintigraphy. http://www.issoonline.com/content/2/1/7 Anastasia Leondi John Koutsikos Cherry Zerva International Seminars in Surgical Oncology 2005, 2:7 2005-03-23T00:00:00Z doi:10.1186/1477-7800-2-7 International Seminars in Surgical Oncology 1477-7800 2 7 2005-03-23T00:00:00Z XML Adhesive capsulitis or frozen shoulder is a common condition characterized by shoulder pain and stiffness. In patients in whom conservative measures have failed, more invasive interventions such as arthrographic or arthroscopic distension can be very effective in relieving symptoms and improving range of movement. However, absolute contraindications to these procedures include the presence of neoplasia around the shoulder girdle. We present five cases referred to our institution where the diagnosis of shoulder joint malignancy was delayed, following prolonged, ineffective treatment for frozen shoulder. These cases highlight the importance of careful review of the radiology and the need for reconsideration of the diagnosis in refractory "frozen shoulder". http://www.issoonline.com/content/2/1/2 Gerald Quan Derek Carr Stephen Schlicht Gerard Powell Peter Choong International Seminars in Surgical Oncology 2005, 2:2 2005-01-12T00:00:00Z doi:10.1186/1477-7800-2-2 International Seminars in Surgical Oncology 1477-7800 2 2 2005-01-12T00:00:00Z XML Background: Nowadays, more breast cancer patients want to have children after the diagnosis of cancer. The purpose of this study is to review the possibility and risks of giving birth among women with breast cancer previously treated by chemotherapy.Case presentationTwo young women aged 28 and 34 respectively, were treated in our clinic for breast cancer, the first (negative hormonal receptors) by surgery, chemotherapy and radiotherapy and the second (positive hormonal receptors) by surgery, radiotherapy and tamoxifen. They both became pregnant, 1 and 8 years after completion of the therapy respectively. Results: Laboratory testing during pregnancy was negative in both cases and after an uneventful course each woman gave birth to a perfectly healthy child. The first patient breastfed her baby for three months, while the second one did not breastfeed her baby at all. Conclusion: Women undergoing chemotherapy for breast cancer can maintain their fertility and get pregnant. Previous chemotherapy for breast cancer does not present any supplementary risks for the child's mental or physical health. http://www.issoonline.com/content/6/1/7 Kontantinos Kontzoglou Michael Stamatakos Sofia Tsaknaki Helen Goga Alkiviades Kostakis Michael Safioleas International Seminars in Surgical Oncology 2009, 6:7 2009-03-02T00:00:00Z doi:10.1186/1477-7800-6-7 International Seminars in Surgical Oncology 1477-7800 6 7 2009-03-02T00:00:00Z XML It has been long established that post-mastectomy radiotherapy reduces the risk of locoregional failure. A survival advantage, however, has only recently been demonstrated. We here provide a review of the literature as regards to the current indications for post-mastectomy radiotherapy. http://www.issoonline.com/content/6/1/5 Maria Vilarino-Varela Yaw Sinn Chin Andreas Makris International Seminars in Surgical Oncology 2009, 6:5 2009-02-09T00:00:00Z doi:10.1186/1477-7800-6-5 International Seminars in Surgical Oncology 1477-7800 6 5 2009-02-09T00:00:00Z XML Background: Idiopathic granulomatous mastitis is an uncommon, benign entity with a diagnosis of exclusion. The typical clinical presentation of idiopathic granulomatous mastitis often mimics infection or malignancy. As a result, histopathological confirmation of idiopathic granulomatous mastitis combined with exclusion of infection, malignancy and other causes of granulomatous disease is absolutely necessary.Case PresentationWe present a case of a young woman with idiopathic granulomatous mastitis, initially mistaken for mastitis as well as breast carcinoma, and successfully treated with a course of corticosteroids. Conclusion: There is no clear clinical consensus regarding the ideal therapeutic management of idiopathic granulomatous mastitis. Treatment options include expectant management with spontaneous remission, corticosteroid therapy, immunosuppressive agents and extensive surgery for refractory cases. http://www.issoonline.com/content/4/1/21 Richard Tuli Brian O'Hara Janet Hines Anne Rosenberg International Seminars in Surgical Oncology 2007, 4:21 2007-07-27T00:00:00Z doi:10.1186/1477-7800-4-21 International Seminars in Surgical Oncology 1477-7800 4 21 2007-07-27T00:00:00Z XML A presacral mass can present a diagnostic dilemma for the surgical oncologist. Differential diagnoses include congenital causes such as teratoma or chordoma, neurological causes such as neurilemoma or neurofibroma or other malignancies such as lymphoma or sarcoma. Diagnosis usually requires imaging such as CT and MRI and tissue biopsy. We present an unusual cause of a presacral mass being extramedullary haematopoiesis, found incidentally in a 71 year old female. Extramedullary haematopoiesis is defined as the production of myeloid and erythroid elements outside of the bone-marrow. This diagnosis is extremely rare in the presacral area especially in a patient with no haematological abnormalities. A review of the literature is presented. http://www.issoonline.com/content/6/1/18 Sina Babazadeh Matthew Broadhead John Slavin Peter Choong International Seminars in Surgical Oncology 2009, 6:18 2009-11-08T00:00:00Z doi:10.1186/1477-7800-6-18 International Seminars in Surgical Oncology 1477-7800 6 18 2009-11-08T00:00:00Z XML Background: Cystosarcoma phylloides (CP) is an extremely rare form of breast cancer with an unpredictable clinical course. The histological characteristics of this neoplasm have not proved to offer much in the estimation of prognosis of these patients.Patients and methodsIn our clinics, in a time period of 38 years, 22 patients with cystosarcoma phylloides were treated. There were 5 cases of malignancy, 15 cases with benign tumors, and two cases histologically characterized as borderline neoplasia. Metastases were manifested in one patient. All patients were on a 5-year follow-up, except in five cases, one operated three years ago and four operated within the last two years. Results: 16 of 22 patients did not present any signs of local recurrence or metastases. There were three patients that manifested local recurrence and underwent supplementary ongectomy or mastectomy and are free of recurrence ever since. One patient with metastatic CP died. Conclusion: Independently of its histopathological behavior, CP is a tumor difficult to be treated. Meticulous follow-up is mandatory in order to manage possible recurrence of the neoplasm. http://www.issoonline.com/content/6/1/6 Michael Stamatakos Sofia Tsaknaki Konstantinos Kontzoglou John Gogas Alkiviades Kostakis Michael Safioleas International Seminars in Surgical Oncology 2009, 6:6 2009-02-20T00:00:00Z doi:10.1186/1477-7800-6-6 International Seminars in Surgical Oncology 1477-7800 6 6 2009-02-20T00:00:00Z XML We report a case of axillary lymphadenopathy thirty years after a decorative tattoo clinically mimicking metastatic melanoma. The importance of relying on histological confirmation of metastatic disease before altering extent of surgery is discussed. The importance of recording presence of decorative tattoos is stressed. http://www.issoonline.com/content/2/1/28 Chris Jack Asha Adwani Hari Krishnan International Seminars in Surgical Oncology 2005, 2:28 2005-12-01T00:00:00Z doi:10.1186/1477-7800-2-28 International Seminars in Surgical Oncology 1477-7800 2 28 2005-12-01T00:00:00Z XML