Peliosis of the spleen: an immune-complex disease?
Gugger M, Gebbers JO.
Institute of Pathology, Kantonsspital Luzern, Switzerland.
AIMS: To determine the pathogenesis of splenic peliosis by further morphological and immunohistochemical examination. METHODS AND RESULTS: Histological, electron microscopic and immunohistochemical examination revealed evidence for an inflammatory genesis of splenic peliosis with destruction of reticular fibres and local deposits of IgG and activated complement C3. CONCLUSION: Our findings indicate that the peliotic lesion in the spleen may be mediated by immune-complex deposits.
Publication Types:
PMID: 9822931 [PubMed - indexed for MEDLINE]